MR differentiation of hepatic haemangioma and hepatocellular carcinoma: value of delayed-phase Gd-DTPA enhanced images

Rofo. 1991 Jun;154(6):621-7. doi: 10.1055/s-2008-1033198.

Abstract

The efficacy of three different approaches (precontrast and delayed-phase postcontrast T1-weighted (T1-W) images, measurement of T2 value, and dynamic FLASH imaging) for differentiation between hepatic haemangiomas and hepatocellular carcinomas, was compared. Most haemangiomas (89%) showed iso- or hypointensity on precontrast T1-W images and hyperintensity on delayed-phase postcontrast T1-W images. By using both pre/postcontrast T1-W images and T2 measurement, 30 out of 32 lesions (94%) were correctly differentiated. The dynamic FLASH imaging did not significantly improve the overall accuracy although it played a critical role in a few problematic cases. It is concluded that the combination of pre/postcontrast T1-W images is a promising approach for differentiation of small hepatic tumours, and plays a complementary role with T2 measurement.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Carcinoma, Hepatocellular / diagnosis*
  • Contrast Media*
  • Diagnosis, Differential
  • False Negative Reactions
  • False Positive Reactions
  • Female
  • Gadolinium DTPA
  • Gadolinium*
  • Hemangioma / diagnosis*
  • Humans
  • Image Enhancement* / methods
  • Liver Neoplasms / diagnosis*
  • Magnetic Resonance Imaging* / instrumentation
  • Magnetic Resonance Imaging* / methods
  • Male
  • Middle Aged
  • Organometallic Compounds*
  • Pentetic Acid*
  • Time Factors

Substances

  • Contrast Media
  • Organometallic Compounds
  • Pentetic Acid
  • Gadolinium
  • Gadolinium DTPA