Studies of the effect of acemannan on retrovirus infections: clinical stabilization of feline leukemia virus-infected cats

Mol Biother. 1991 Mar;3(1):41-5.

Abstract

Feline leukemia is a disease induced by an oncornavirus infection that inevitably causes clinically affected cats to die. It has been estimated that 40% of cats are dead within 4 weeks and 70% within 8 weeks of the onset of clinical symptoms. Acemannan is a complex carbohydrate with both immunostimulatory and direct antiviral properties. Administration of acemannan for 6 weeks intraperitoneally to clinically symptomatic cats significantly improved both the quality of life and the survival rate. Twelve weeks after initiation of treatment, 71% of treated cats were alive and in good health.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adjuvants, Immunologic / administration & dosage
  • Adjuvants, Immunologic / therapeutic use
  • Animals
  • Cat Diseases / drug therapy*
  • Cats
  • Injections, Intraperitoneal
  • Leukemia / drug therapy
  • Leukemia / veterinary*
  • Leukemia Virus, Feline*
  • Mannans / administration & dosage
  • Mannans / therapeutic use*

Substances

  • Adjuvants, Immunologic
  • Mannans
  • acemannan