Abstract
We report the case of a 19-year-old pregnant woman who presented with a nipple tumor. The lesion consisted in a spindle-cell proliferation with histologic features similar to those of fibrous histiocytoma, with a highly vascularized stroma. Although it showed low mitotic activity, scattered marked atypical cells with prominent nucleoli were identified, thus raising concern about the benign nature of the tumor. Immunohistochemical evaluation revealed that the spindle cells were diffusely positive for vimentin, focally positive for CD68, and negative for all the other tested antibodies. The patient had a total excision of the lesion and she is free of disease after 30 months. To our knowledge this is the first reported case of a lesion of this type in the nipple after body-piercing.
Int J Surg Pathol 14(1):89-93, 2006.
Publication types
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Case Reports
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Research Support, Non-U.S. Gov't
MeSH terms
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Adult
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Antigens, CD / analysis
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Antigens, Differentiation, Myelomonocytic / analysis
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Body Piercing / adverse effects*
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Breast Neoplasms / chemistry
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Breast Neoplasms / diagnosis*
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Breast Neoplasms / etiology*
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Breast Neoplasms / pathology
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Cell Proliferation
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Female
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Histiocytoma, Benign Fibrous / chemistry
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Histiocytoma, Benign Fibrous / diagnosis*
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Histiocytoma, Benign Fibrous / etiology*
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Histiocytoma, Benign Fibrous / pathology
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Humans
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Immunohistochemistry
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Nipples / chemistry
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Nipples / pathology*
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Nipples / surgery
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Pregnancy
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Pregnancy Complications, Neoplastic / diagnosis*
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Pregnancy Complications, Neoplastic / etiology
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Pregnancy Complications, Neoplastic / pathology
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Vimentin / analysis
Substances
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Antigens, CD
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Antigens, Differentiation, Myelomonocytic
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CD68 antigen, human
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Vimentin