Starving the malaria parasite: inhibitors active against the aspartic proteases plasmepsins I, II, and IV

MeSH terms

• Animals
• Antimalarials / chemical synthesis
• Antimalarials / chemistry
• Aspartic Acid Endopeptidases / antagonists & inhibitors*
• Binding Sites
• Cathepsins / antagonists & inhibitors
• Humans
• Malaria / drug therapy*
• Models, Chemical
• Models, Molecular
• Plasmodium / enzymology*
• Protease Inhibitors / chemical synthesis
• Protease Inhibitors / chemistry
• Protein Binding
• Protozoan Proteins
• Structure-Activity Relationship