An autopsy case of necrotizing ventriculo-encephalitis caused by cytomegalovirus in Hodgkin's disease

Acta Pathol Jpn. 1991 Apr;41(4):291-8. doi: 10.1111/j.1440-1827.1991.tb03358.x.

Abstract

A 59-year-old Japanese woman with Hodgkin's disease developed progressive dementia and died of pneumonia. The autopsy revealed necrotizing ventriculo-encephalitis caused by cytomegalovirus (CMV) infection, which was confirmed by immunohistochemical and electron microscopic examinations. It is suggested that CMV ventriculo-encephalitis could occur not only in patients with acquired immunodeficiency syndrome, but also in other immunocompromised hosts.

Publication types

  • Case Reports

MeSH terms

  • Autopsy
  • Cerebral Ventricles / microbiology*
  • Cerebral Ventricles / pathology
  • Cerebral Ventricles / ultrastructure
  • Cytomegalovirus / isolation & purification
  • Cytomegalovirus / physiology*
  • Cytomegalovirus Infections / complications
  • Cytomegalovirus Infections / microbiology
  • Cytomegalovirus Infections / pathology*
  • Encephalitis / etiology
  • Encephalitis / microbiology*
  • Encephalitis / pathology
  • Female
  • Hodgkin Disease / complications
  • Hodgkin Disease / microbiology
  • Hodgkin Disease / pathology*
  • Humans
  • Immunohistochemistry
  • Microscopy, Electron
  • Middle Aged
  • Necrosis