Abstract
Combination therapy with steroids and azathioprine is the reference treatment for autoimmune hepatitis, but potential adverse effects are numerous and intolerance can occur. We report a patient with a well-documented type 1 autoimmune hepatitis intolerant to corticosteroids and azathioprine therapy, in whom eight years of ursodeoxycholic acid monotherapy was associated with biochemical and histological remission.
MeSH terms
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Adrenal Cortex Hormones / pharmacology
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Adult
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Azathioprine / therapeutic use
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Cholagogues and Choleretics / therapeutic use*
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Drug Resistance
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Female
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Hepatitis, Autoimmune / drug therapy*
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Hepatitis, Autoimmune / pathology
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Humans
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Immunosuppressive Agents / therapeutic use
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Treatment Outcome
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Ursodeoxycholic Acid / therapeutic use*
Substances
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Adrenal Cortex Hormones
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Cholagogues and Choleretics
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Immunosuppressive Agents
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Ursodeoxycholic Acid
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Azathioprine