Abstract
Characterisation of recombinant Streptomyces spheroides NovW in vitro suggests that it is not a kinetically competent dual action dTDP-6-deoxy-d-xylo-4-hexulose 3,5-epimerase, but possesses only significant 3-epimerase activity.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
MeSH terms
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Carbohydrate Epimerases / chemistry
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Carbohydrate Epimerases / metabolism*
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Catalysis
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Kinetics
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Models, Molecular
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Molecular Structure
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Novobiocin / biosynthesis
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Novobiocin / chemistry
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Solvents
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Streptomyces / chemistry*
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Streptomyces / enzymology*
Substances
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Solvents
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Novobiocin
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Carbohydrate Epimerases