Abstract
We demonstrate the self-assembly of DNA and DNA binding proteins into two-dimensional networks that are then addressable by sending a second protein to a specific recognition site on the DNA network. These networks cover centimeters in area but can be addressed with nanometer precision. This hierarchical self-assembly of specific DNA protein complexes will be the basis for complex positioning of single molecules in two and three dimensions.
Publication types
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Base Sequence
-
DNA / chemistry
-
DNA / metabolism*
-
DNA / ultrastructure*
-
Microscopy, Atomic Force
-
Models, Molecular
-
NF-kappa B / chemistry
-
NF-kappa B / metabolism
-
NF-kappa B / ultrastructure
-
Nanostructures / chemistry*
-
Nucleic Acid Conformation
-
Protein Binding
-
Protein Structure, Quaternary
-
Proteins / chemistry
-
Proteins / metabolism*
-
Proteins / ultrastructure*
-
Spectrum Analysis