Objective: To comment on the recent advances of production and application of the bio-derived scaffold in the tissue engineered peripheral nerve.
Methods: The recent articles were systematically analyzed, and then the production methods of the bio-derived scaffold and its application to the tissue engineered peripheral nerve were evaluated and prospected.
Results: Biological tissues were processed by some methods to produce the bio-derived materials. These materials could maintain the structure and components of the tissues. Moreover; the immunogenicity of these materials was reduced.
Conclusion: Application of the bio-derived materials is a trend in the fabricating scaffold of the tissue engineered peripheral nerve.