Abstract
Non-Hodgkin's lymphoma (NHL) refers to a heterogeneous group of lymphoproliferative diseases with a diversity of clinical courses, including involvement in another organs. NHL frequently involves the thoracic structures, and particularly the mediastinum and lung parenchyma. Several clinical reports have described bronchial-associated lymphoid tissue (BALT) lymphoma as an endobronchial lesion, but endobronchial infiltration with diffuse large B-cell lymphoma is extremely rare. Here, we provide the first report of this condition confirmed by a histopathological study and the presence of an immunoglobulin heavy chain (IgH) gene rearrangement detected by a polymerase chain reaction (PCR).
MeSH terms
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Antibodies, Monoclonal / administration & dosage
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Antibodies, Monoclonal, Murine-Derived
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Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
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Base Sequence
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Bronchial Neoplasms / diagnostic imaging
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Bronchial Neoplasms / drug therapy
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Bronchial Neoplasms / genetics
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Bronchial Neoplasms / pathology*
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Carboplatin / administration & dosage
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DNA Primers
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Etoposide / administration & dosage
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Gene Rearrangement
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Humans
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Ifosfamide / administration & dosage
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Immunoglobulin Heavy Chains / genetics
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Lymphoma, B-Cell / diagnostic imaging
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Lymphoma, B-Cell / drug therapy
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Lymphoma, B-Cell / genetics
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Lymphoma, B-Cell / pathology*
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Male
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Middle Aged
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Rituximab
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Tomography, X-Ray Computed
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Treatment Outcome
Substances
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Antibodies, Monoclonal
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Antibodies, Monoclonal, Murine-Derived
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DNA Primers
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Immunoglobulin Heavy Chains
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Rituximab
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Etoposide
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Carboplatin
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Ifosfamide