Severe progressive late onset myelopathy and arachnoiditis following neonatal meningitis

Eur J Paediatr Neurol. 2006 Jan;10(1):31-6. doi: 10.1016/j.ejpn.2005.10.001. Epub 2006 Mar 15.

Abstract

This case series describes four children who had meningitis in the neonatal period. After a stable period of years, they developed a myelopathy caused by chronic arachnoiditis. The myelopathy was precipitated by a fall in two cases, and in two cases there was an acute deterioration after surgery. A history of neonatal meningitis should be taken into consideration before planning surgery or anaesthesia. Careful intra-operative positioning, immobilisation of the neck, and maintenance of blood pressure is important but may not prevent this complication.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Arachnoiditis / etiology*
  • Arachnoiditis / pathology
  • Arachnoiditis / surgery
  • Fatal Outcome
  • Female
  • Humans
  • Hydrocephalus / complications
  • Hydrocephalus / pathology
  • Infant, Newborn
  • Magnetic Resonance Imaging
  • Male
  • Meningitis, Bacterial / complications*
  • Meningitis, Escherichia coli / complications
  • Meningitis, Escherichia coli / pathology
  • Meningitis, Pneumococcal / complications
  • Meningitis, Pneumococcal / pathology
  • Neurosurgical Procedures
  • Spinal Cord / pathology
  • Spinal Cord Diseases / etiology*
  • Spinal Cord Diseases / pathology
  • Spinal Cord Diseases / surgery
  • Tomography, X-Ray Computed
  • Ventriculoperitoneal Shunt