Abstract
The complete nucleotide sequences of the matrix protein (M) genes of parainfluenza virus types 4A and 4B (PIV-4A and -4B) were determined from cDNA of the mRNA, and found to be 1548 bases in length, exclusive of poly(A) sequences. The sequences contained a large open reading frame of 1146 nucleotides encoding 362 amino acids. A high degree of identity (96.1%) was observed between the amino acid sequences of PIV-4A and PIV-4B M. These M sequences were compared with those of 10 other paramyxoviruses and a phylogenetic tree was constructed.
MeSH terms
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Amino Acid Sequence
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Base Sequence
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Cross Reactions
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DNA, Viral / chemistry*
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Gene Library
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Humans
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Molecular Sequence Data
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Open Reading Frames
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Phylogeny
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RNA, Messenger / chemistry*
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RNA, Viral / chemistry*
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Respirovirus / classification
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Respirovirus / genetics*
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Viral Matrix Proteins / chemistry
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Viral Matrix Proteins / genetics*
Substances
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DNA, Viral
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RNA, Messenger
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RNA, Viral
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Viral Matrix Proteins
Associated data
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GENBANK/D00931
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GENBANK/D00932
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GENBANK/D01050
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GENBANK/D01051
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GENBANK/D10241
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GENBANK/D10242
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GENBANK/M59339
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GENBANK/M59340
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GENBANK/M59341
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GENBANK/M59342
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GENBANK/M59343
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GENBANK/M59344