Corticosteroids combined with continuous veno-venous hemodiafiltration for treatment of hantavirus pulmonary syndrome caused by Puumala virus infection

E Seitsonen; M Hynninen; E Kolho; H Kallio-Kokko; V Pettilä

doi:10.1007/s10096-006-0117-z

Corticosteroids combined with continuous veno-venous hemodiafiltration for treatment of hantavirus pulmonary syndrome caused by Puumala virus infection

Eur J Clin Microbiol Infect Dis. 2006 Apr;25(4):261-6. doi: 10.1007/s10096-006-0117-z.

Authors

E Seitsonen¹, M Hynninen, E Kolho, H Kallio-Kokko, V Pettilä

Affiliation

¹ Department of Anesthesiology and Intensive Care Medicine, Helsinki University Central Hospital, Stenbäckinkatu 11, P.O. B 281, 00029 HUS, Helsinki, Finland. [email protected]

Abstract

Reported here are two cases of hantavirus pulmonary syndrome caused by Puumala virus infection, which rapidly resolved after initiation of corticosteroid treatment combined with continuous veno-venous hemodiafiltration. These cases emphasize the role of the inflammatory response in the pathogenesis of hantavirus pulmonary syndrome.

Publication types

Case Reports
Research Support, Non-U.S. Gov't

MeSH terms

Adrenal Cortex Hormones / therapeutic use*
Adult
Aged
Combined Modality Therapy
Hantavirus Pulmonary Syndrome / diagnostic imaging
Hantavirus Pulmonary Syndrome / etiology
Hantavirus Pulmonary Syndrome / therapy*
Hemofiltration*
Hemorrhagic Fever with Renal Syndrome / complications
Hemorrhagic Fever with Renal Syndrome / diagnostic imaging
Hemorrhagic Fever with Renal Syndrome / therapy*
Humans
Male
Puumala virus* / isolation & purification
Radiography

Substances

Adrenal Cortex Hormones