Disseminated histoplasmosis in an AIDS patient treated with itraconazole

P D Kell; D E Smith; S E Barton; J Midgley; P L Samarasinghe; B G Gazzard

doi:10.1136/sti.67.4.342

Disseminated histoplasmosis in an AIDS patient treated with itraconazole

Genitourin Med. 1991 Aug;67(4):342-4. doi: 10.1136/sti.67.4.342.

Authors

P D Kell¹, D E Smith, S E Barton, J Midgley, P L Samarasinghe, B G Gazzard

Affiliation

¹ Department of Genitourinary Medicine, St. Stephen's Clinic & Westminster Hospital.

Abstract

A patient with AIDS presented with a fever, shortness of breath and a productive cough. A provisional diagnosis of Pneumocystis carinii pneumonia was made; however, blood cultures and bone marrow examination revealed disseminated infection with Histoplasmosis capsulatum. This was treated by itraconazole with initial success, but the patient relapsed while on maintenance therapy.

Publication types

Case Reports

MeSH terms

Acquired Immunodeficiency Syndrome / complications*
Acquired Immunodeficiency Syndrome / drug therapy
Acquired Immunodeficiency Syndrome / microbiology
Adult
Antifungal Agents / therapeutic use*
Blood / microbiology
Histoplasma* / isolation & purification
Histoplasmosis / complications*
Humans
Itraconazole
Ketoconazole / analogs & derivatives*
Ketoconazole / therapeutic use
Macrophages / microbiology
Male
Opportunistic Infections / complications*
Opportunistic Infections / microbiology

Substances

Antifungal Agents
Itraconazole
Ketoconazole