Abstract
The effect of abamectin (ABM) on rainbow trout (Oncorhynchus mykiss) was studied. The acute toxicity of ABM on rainbow trout was established, following the target 58-h water bath exposure of ABM concentrations from 0.6 to 4.5 microg/l, on the basis of which LD75 (4.0 microg/l) was calculated. The histological changes in organs showed a direct toxicity of ABM for rainbow trout since degenerative changes in brain and kidney and--to a minor extent--in liver were established. The values of the ABM residues in fish muscle tissue with skin were proportional to the exposed concentrations of ABM.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Brain / drug effects
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Brain / pathology
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Insecticides / pharmacokinetics
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Insecticides / toxicity*
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Ivermectin / analogs & derivatives*
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Ivermectin / pharmacokinetics
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Ivermectin / toxicity
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Kidney / drug effects
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Kidney / pathology
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Liver / drug effects
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Liver / pathology
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Muscle, Skeletal / metabolism
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Oncorhynchus mykiss* / growth & development
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Oncorhynchus mykiss* / metabolism
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Organ Specificity
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Pesticide Residues / pharmacokinetics
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Pesticide Residues / toxicity*
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Skin / metabolism
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Tissue Distribution
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Toxicity Tests, Acute
Substances
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Insecticides
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Pesticide Residues
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abamectin
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Ivermectin