Epigenetic disruption of two proapoptotic genes MAPK10/JNK3 and PTPN13/FAP-1 in multiple lymphomas and carcinomas through hypermethylation of a common bidirectional promoter

Leukemia. 2006 Jun;20(6):1173-5. doi: 10.1038/sj.leu.2404193.

Authors

J Ying, H Li, Y Cui, A H Y Wong, C Langford, Q Tao

PMID: 16572203
DOI: 10.1038/sj.leu.2404193

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Carcinoma / genetics*
Cell Line, Tumor
Chromosomes, Human, Pair 4 / genetics
DNA Methylation*
Gene Silencing
Humans
Lymphoma / genetics*
Mitogen-Activated Protein Kinase 10 / genetics*
Mitogen-Activated Protein Kinase 10 / metabolism
Oligonucleotide Array Sequence Analysis
Promoter Regions, Genetic*
Protein Tyrosine Phosphatase, Non-Receptor Type 13
Protein Tyrosine Phosphatases / genetics*
Protein Tyrosine Phosphatases / metabolism
Reverse Transcriptase Polymerase Chain Reaction
Sensitivity and Specificity
Tumor Suppressor Proteins / genetics
Tumor Suppressor Proteins / metabolism

Substances

Tumor Suppressor Proteins
Mitogen-Activated Protein Kinase 10
PTPN13 protein, human
Protein Tyrosine Phosphatase, Non-Receptor Type 13
Protein Tyrosine Phosphatases