Abstract
This study describes the initial data concerning molecular typing of Pneumocystis jirovecii in a patient having developed granulomatous Pneumocystis pneumonia (PCP). Three types, B(1)a(3), B(1)a(4), B(1)b(2), were identified. All three had been described in reports concerning patients with common diffuse alveolar PCP. The present data show that identical microorganisms can be involved in both granulomatous PCP and diffuse alveolar PCP and that the pathogenesis of the granulomatous response to P. jirovecii may more likely be related to host factors.
Publication types
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Case Reports
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Research Support, Non-U.S. Gov't
MeSH terms
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Bacterial Typing Techniques
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Fatal Outcome
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Genes, Bacterial
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Genotype
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Granuloma / complications
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Granuloma / microbiology*
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Humans
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Immunocompromised Host
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Leukemia, Lymphocytic, Chronic, B-Cell / complications*
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Male
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Middle Aged
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Pneumocystis carinii / classification
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Pneumocystis carinii / genetics
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Pneumocystis carinii / isolation & purification*
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Pneumonia, Pneumocystis / classification
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Pneumonia, Pneumocystis / complications
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Pneumonia, Pneumocystis / microbiology*
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Pneumonia, Pneumocystis / pathology