Abstract
Spinal anaesthesia for caesarean delivery may be associated with hypotension and fetal acidosis. Prophylactic infusion of phenylephrine (PE) immediately after the induction of anaesthesia appears to be a more effective approach than administration of ephedrine to reduce the incidence, frequency and severity of hypotension. Furthermore, PE appears to be associated with better fetal acid-base status than is ephedrine.
Publication types
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Comparative Study
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English Abstract
MeSH terms
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Acidosis / prevention & control
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Adrenergic alpha-Agonists / administration & dosage*
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Adrenergic alpha-Agonists / adverse effects
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Anesthesia, Obstetrical* / adverse effects
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Anesthesia, Spinal* / adverse effects
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Cesarean Section*
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Ephedrine / administration & dosage*
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Ephedrine / adverse effects
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Female
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Humans
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Hypotension / prevention & control
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Infant, Newborn
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Infusions, Intravenous
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Phenylephrine / administration & dosage*
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Phenylephrine / adverse effects
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Pregnancy
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Vasoconstrictor Agents / administration & dosage*
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Vasoconstrictor Agents / adverse effects
Substances
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Adrenergic alpha-Agonists
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Vasoconstrictor Agents
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Phenylephrine
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Ephedrine