[From cancer to diabetes treatment : the tumor suppressor LKB1 as a new pharmacological target]

MeSH terms

• AMP-Activated Protein Kinase Kinases
• AMP-Activated Protein Kinases
• Animals
• Cyclic AMP Response Element-Binding Protein / physiology
• Cyclic AMP-Dependent Protein Kinases / physiology
• Diabetes Mellitus, Experimental / drug therapy
• Diabetes Mellitus, Experimental / metabolism
• Diabetes Mellitus, Type 2 / drug therapy*
• Diabetes Mellitus, Type 2 / metabolism
• Diabetes Mellitus, Type 2 / prevention & control
• Enzyme Activation / drug effects
• Fasting / metabolism
• Gene Expression Regulation / drug effects*
• Genes, Tumor Suppressor* / drug effects
• Gluconeogenesis / drug effects
• Gluconeogenesis / physiology*
• Hepatocytes / drug effects
• Hepatocytes / metabolism
• Homeostasis
• Humans
• Hypoglycemic Agents / pharmacology*
• Insulin Resistance
• Liver / drug effects*
• MAP Kinase Signaling System / drug effects
• Metformin / pharmacology*
• Mice
• Mice, Knockout
• Models, Biological
• Multienzyme Complexes / physiology
• Neoplasms / prevention & control*
• Peutz-Jeghers Syndrome / genetics
• Phosphoproteins / physiology
• Protein Serine-Threonine Kinases / deficiency
• Protein Serine-Threonine Kinases / genetics
• Protein Serine-Threonine Kinases / physiology*
• Transcription Factors