Abstract
According to IR, UV, MS and NMR spectra of the compounds isolated from the fresh stem of Dendrobium loddigesii Rolfe (a Chinese medicine), 3 constituents were identified. They are shihunidine, shihunine and dendrophenol (4,4'- dihydroxy-3,3',5-trimethoxybibenzyl). Chemical reactions showed that shihunidine was derived from shihunine during isolation. Shihunidine and shihunine were shown to be inhibitors of Na+, K+-ATPase of the rat kidney.
MeSH terms
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Animals
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Benzyl Compounds / chemistry
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Benzyl Compounds / isolation & purification*
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Isoindoles
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Kidney / enzymology
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Lactones / chemistry
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Lactones / isolation & purification*
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Microsomes / enzymology
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Plants, Medicinal / chemistry*
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Pyrrolidines / chemistry
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Pyrrolidines / isolation & purification*
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Rats
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Sodium-Potassium-Exchanging ATPase / metabolism
Substances
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Benzyl Compounds
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Isoindoles
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Lactones
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Pyrrolidines
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dendrophenol
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shihunidine
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shihunine
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Sodium-Potassium-Exchanging ATPase