Is it time to abandon microsatellite instability as a pre-screen for selecting families for mutation testing for mismatch repair genes?

J Clin Oncol. 2006 Apr 20;24(12):1960-2; author reply 1962-3. doi: 10.1200/JCO.2005.05.3207.
No abstract available

Publication types

  • Comment
  • Letter

MeSH terms

  • Base Pair Mismatch
  • Chromosomal Instability*
  • Cost-Benefit Analysis
  • DNA Mutational Analysis / economics
  • DNA Repair / genetics*
  • Genetic Testing*
  • Germ-Line Mutation
  • Humans
  • Immunohistochemistry
  • Microsatellite Repeats*
  • Neoplasms / etiology
  • Neoplasms / genetics
  • Pedigree
  • Risk Factors