Cerebellar metastasis from pancreatic adenocarcinoma. A case report

Pancreatology. 2006;6(4):306-8. doi: 10.1159/000092693. Epub 2006 Apr 19.

Abstract

The first discovery of a cerebellar metastasis of pancreatic carcinoma in a living patient is described. Two years earlier the patient had undergone a pancreaticoduodenectomy for an adenocarcinoma of the head of the pancreas with a lymph node metastasis. After complete surgical removal of the tumor, he underwent adjuvant chemoradiation. Two years later the patient presented with intractable vomiting, which was attributed to peritoneal carcinomatosis. Clinical evaluation revealed an intracranial tumor without signs of pancreatic recurrence. The tumor was surgically removed. One year later the patient developed multiple brain metastases and he is currently undergoing gemcitabine-based chemotherapy.

Publication types

  • Case Reports

MeSH terms

  • Adenocarcinoma / secondary*
  • Adenocarcinoma / surgery
  • Aged
  • Antimetabolites, Antineoplastic / therapeutic use
  • Cerebellar Neoplasms / diagnostic imaging*
  • Cerebellar Neoplasms / drug therapy
  • Cerebellar Neoplasms / secondary*
  • Deoxycytidine / analogs & derivatives
  • Deoxycytidine / therapeutic use
  • Gemcitabine
  • Humans
  • Male
  • Pancreatic Neoplasms / pathology*
  • Pancreatic Neoplasms / surgery
  • Pancreaticoduodenectomy
  • Recurrence
  • Tomography, X-Ray Computed

Substances

  • Antimetabolites, Antineoplastic
  • Deoxycytidine
  • Gemcitabine