Increasing prevalence and diversity of metallo-beta-lactamases in Pseudomonas spp., Acinetobacter spp., and Enterobacteriaceae from Korea

Antimicrob Agents Chemother. 2006 May;50(5):1884-6. doi: 10.1128/AAC.50.5.1884-1886.2006.

Abstract

Among imipenem-nonsusceptible isolates, acquired metallo-beta-lactamase genes were detected in 36 of 581 (6.2%) Pseudomonas aeruginosa isolates, 42 of 44 (95.4%) other Pseudomonas species, and 136 of 513 (26.5%) Acinetobacter species from 2003 to 2004 at a Korean hospital. Overall, bla(VIM-2)-like genes were the most prevalent and were also detected in Enterobacteriaceae, including Klebsiella pneumoniae.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acinetobacter / classification
  • Acinetobacter / enzymology*
  • Acinetobacter / genetics
  • Acinetobacter / growth & development
  • Acinetobacter / isolation & purification
  • Enterobacteriaceae / enzymology*
  • Enterobacteriaceae / genetics
  • Enterobacteriaceae / growth & development
  • Enterobacteriaceae / isolation & purification
  • Genes, Bacterial
  • Genetic Variation*
  • Humans
  • Korea / epidemiology
  • Prevalence*
  • Pseudomonas / classification
  • Pseudomonas / enzymology*
  • Pseudomonas / genetics
  • Pseudomonas / growth & development
  • Pseudomonas / isolation & purification
  • Sputum / microbiology
  • Urine / microbiology
  • beta-Lactamases / genetics*

Substances

  • beta-Lactamases