Successful treatment of intracardiac progression and metachronous multiple brain metastases from primary lung cancer

Jpn J Thorac Cardiovasc Surg. 2006 Apr;54(4):168-70. doi: 10.1007/BF02662473.

Abstract

We report a rare case of squamous cell carcinoma of the lung extending into the left atrium via the pulmonary vein. The tumor tissue including the thrombus was resected en-bloc under cardiopulmonary bypass. Despite adjuvant chemotherapy, multiple brain metastases developed, but they were eradicated by stereotactic radiosurgery. The patient is still disease-free 48 months after the resection. This case serves to demonstrate the validity of multidisciplinary treatment for locally advanced lung cancer.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Brain Neoplasms / secondary
  • Brain Neoplasms / surgery*
  • Carboplatin / administration & dosage
  • Carcinoma, Squamous Cell / secondary
  • Carcinoma, Squamous Cell / therapy*
  • Cardiopulmonary Bypass
  • Chemotherapy, Adjuvant
  • Female
  • Heart Atria / pathology
  • Heart Atria / surgery
  • Heart Neoplasms / secondary
  • Heart Neoplasms / therapy*
  • Humans
  • Lung Neoplasms / pathology*
  • Lung Neoplasms / therapy*
  • Neoplasms, Second Primary / secondary
  • Neoplasms, Second Primary / therapy*
  • Pulmonary Veins / pathology
  • Pulmonary Veins / surgery
  • Radiosurgery
  • Vinblastine / administration & dosage
  • Vinblastine / analogs & derivatives
  • Vinorelbine

Substances

  • Vinblastine
  • Carboplatin
  • Vinorelbine