The aim of the present study was the evaluation of physical activity likely to lead to the onset of life-threatening ventricular arrhythmias in subjects affected by arrhythmogenic right ventricular cardiomyopathy. In particular, strenuous physical activity can be dangerous in patients with minor or 'concealed' forms of the disease, in whom no previous diagnosis has been made. In these patients preventive strategies cannot be adopted due to the lack of a clinical diagnosis, and so physical effort can be responsible for the first noticeable symptom of the disease.