Glucose challenge test threshold values in screening for gestational diabetes among black women

Am J Obstet Gynecol. 2006 May;194(5):e46-8. doi: 10.1016/j.ajog.2006.03.051.

Abstract

Objective: The objective of the study was to assess the incidence of gestational diabetes among black women according to various cut-off values of the glucose challenge test.

Study design: We performed a retrospective chart review of black patients who had a 50-g, 1-hour glucose challenge test between 24 and 28 weeks' gestation of 130 mg/dL or higher followed by a 100-g, 3-hour glucose tolerance test. Results were categorized in 10-mg/dL increments. Gestational diabetes was diagnosed by 2 or more abnormal values using the Carpenter-Coustan criteria.

Results: The study included 387 patients. The incidence of gestational diabetes diagnosed overall in all patients with a glucose challenge test of 130 mg/dL or higher was 31.2%. The incidence of gestational diabetes in individuals with a challenge test in the range of 130 to 140 mg/dL was 10.7%. The incidence of gestational diabetes with a screening test of 180 mg/dL or higher was 72.0%.

Conclusion: Our data support the use of 130 mg/dL as the threshold for a positive glucose challenge test and suggest the use of a glucose tolerance test to confirm the diagnosis of gestational diabetes for screening values up to 200 mg/dL.

Publication types

  • Evaluation Study

MeSH terms

  • Adult
  • Black People / statistics & numerical data*
  • Diabetes, Gestational / diagnosis*
  • Diabetes, Gestational / epidemiology*
  • Differential Threshold
  • Female
  • Glucose*
  • Humans
  • Incidence
  • Mass Screening / methods*
  • Mass Screening / standards
  • Pregnancy

Substances

  • Glucose