Isorhamnetin glycosides with free radical and ONOO-scavenging activities from the stamens of Nelumbo nucifera

Arch Pharm Res. 2006 Apr;29(4):287-92. doi: 10.1007/BF02968572.

Abstract

In this study, we isolated two new isorhamnetin glycosides, designated as nelumboroside A (3) and nelumboroside B (4), as well as the previously-characterized isorhamnetin glucoside (1) and isorhamnetin rutinoside (2), from the n-BuOH fraction of Nelumbo nucifera stamens. The structures of the two new compounds were then determined, using chemical and spectroscopic techniques. All isolated isorhamnetin glycosides 1-4 showed marked antioxidant activities in the DPPH, and ONOO- assays.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Biphenyl Compounds / chemistry
  • Flavonols / chemistry
  • Flavonols / isolation & purification*
  • Flowers / chemistry
  • Free Radical Scavengers / chemistry
  • Free Radical Scavengers / isolation & purification*
  • Glycosides / chemistry
  • Glycosides / isolation & purification*
  • Hydrazines / chemistry
  • Nelumbo / chemistry*
  • Peroxynitrous Acid / chemistry
  • Picrates
  • Quercetin / analogs & derivatives

Substances

  • Biphenyl Compounds
  • Flavonols
  • Free Radical Scavengers
  • Glycosides
  • Hydrazines
  • Picrates
  • 3-methylquercetin
  • Peroxynitrous Acid
  • Quercetin
  • 1,1-diphenyl-2-picrylhydrazyl