[The induction of CYP3A regulated by pregnane X receptor and its significance in drug metabolism]

Yao Xue Xue Bao. 2006 Jan;41(1):1-6.
[Article in Chinese]
No abstract available

Publication types

  • Review

MeSH terms

  • Animals
  • Bridged Bicyclo Compounds / metabolism
  • Constitutive Androstane Receptor
  • Cytochrome P-450 CYP3A / biosynthesis*
  • Cytochrome P-450 CYP3A / genetics
  • Drug Design
  • Drug Interactions
  • Enzyme Induction
  • Humans
  • Lithocholic Acid / metabolism
  • Phloroglucinol / analogs & derivatives
  • Phloroglucinol / metabolism
  • Pregnane X Receptor
  • Receptors, Cytoplasmic and Nuclear / genetics
  • Receptors, Cytoplasmic and Nuclear / metabolism
  • Receptors, Cytoplasmic and Nuclear / physiology*
  • Receptors, Steroid / genetics
  • Receptors, Steroid / physiology*
  • Signal Transduction
  • Terpenes / metabolism
  • Transcription Factors / genetics
  • Transcription Factors / metabolism

Substances

  • Bridged Bicyclo Compounds
  • Constitutive Androstane Receptor
  • Pregnane X Receptor
  • Receptors, Cytoplasmic and Nuclear
  • Receptors, Steroid
  • Terpenes
  • Transcription Factors
  • Lithocholic Acid
  • Phloroglucinol
  • Cytochrome P-450 CYP3A
  • hyperforin