Life events exposure before a treated major depressive episode depends on the number of past episodes

Emmanuelle Corruble; Bruno Falissard; Philip Gorwood

doi:10.1016/j.eurpsy.2006.03.006

Life events exposure before a treated major depressive episode depends on the number of past episodes

Eur Psychiatry. 2006 Sep;21(6):364-6. doi: 10.1016/j.eurpsy.2006.03.006. Epub 2006 May 11.

Authors

Emmanuelle Corruble¹, Bruno Falissard, Philip Gorwood

Affiliation

¹ Department of Psychiatry, Assistance Publique-Hôpitaux de Paris, Bicêtre University Hospital, INSERM U 669, Paris XI University, 78 rue du General Leclerc, 94230 Le Kremlin Bicêtre, France. [email protected]

PMID: 16690262
DOI: 10.1016/j.eurpsy.2006.03.006

Abstract

A cross-sectional survey investigated the relationship between the number of previous depressive episodes and life events, testing the kindling hypothesis, in a sample of 13,377 treated patients with unipolar depression. A linear decline of average life events exposure is observed for more frequent past episodes, even when age, gender and severity are taken into account.

MeSH terms

Adult
Cross-Sectional Studies
Depressive Disorder, Major* / epidemiology
Depressive Disorder, Major* / psychology
Depressive Disorder, Major* / therapy
Female
Humans
Incidence
Kindling, Neurologic*
Life Change Events*
Male
Middle Aged
Prevalence
Psychological Theory
Recurrence
Stress, Psychological / epidemiology
Stress, Psychological / psychology
Surveys and Questionnaires
Time Factors