Cerebral blood flow after ventriculoperitoneal shunt in children with hydrocephalus

Childs Nerv Syst. 1990 Nov;6(7):388-91. doi: 10.1007/BF00302224.

Abstract

Fourteen hydrocephalic children were studied who were between the ages of 6 months and 14 years. Regional cerebral blood flow (rCBF) was measured by the 133Xe intravenous injection method after ventriculoperitoneal shunting. There was a negative correlation between slow flow and preoperative ventricular size (r = -0.718, P < 0.02), but there was no correlation between fast flow and preoperative ventricular size. There was also no correlation between rCBF and postoperative ventricular size. Postoperative IQ or development quotient showed a positive correlation with slow flow (r = 0.813, P < 0.01), but not with fast flow. It is suggested that in hydrocephalic children there is impairment of white-matter communicating fibres and secondary reduction in higher intellectual activity.

MeSH terms

  • Adolescent
  • Blood Flow Velocity / physiology
  • Brain / blood supply*
  • Child
  • Child, Preschool
  • Female
  • Humans
  • Hydrocephalus / diagnostic imaging
  • Hydrocephalus / surgery*
  • Infant
  • Male
  • Postoperative Complications / diagnostic imaging*
  • Radionuclide Imaging
  • Regional Blood Flow / physiology
  • Ventriculoperitoneal Shunt*
  • Xenon Radioisotopes

Substances

  • Xenon Radioisotopes