Abstract
A mixed glioma and sarcoma in a 3-month-old infant is presented as a rare case of gliosarcoma with a good response to treatment. This congenital case is quite different from those in adults: the tumor cells were mainly composed of sarcomatous elements; glial components were not anaplastic without obvious endothelial hyperplasia, but presented as reticulin-free islands, mimicking a reactive glioma in a sarcoma. It may be termed "sarcoglioma" to distinguish from a classic gliosarcoma. The origin of the rare mixed tumor may be related to a dysgenesis of both mesenchymal and glial elements.
MeSH terms
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Basal Ganglia / pathology
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Basal Ganglia Diseases / pathology
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Basal Ganglia Diseases / surgery*
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Brain Neoplasms / congenital*
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Brain Neoplasms / pathology
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Brain Neoplasms / radiotherapy
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Brain Neoplasms / surgery
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Combined Modality Therapy
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Cranial Irradiation
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Female
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Follow-Up Studies
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Glial Fibrillary Acidic Protein / analysis
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Gliosarcoma / congenital*
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Gliosarcoma / pathology
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Gliosarcoma / radiotherapy
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Gliosarcoma / surgery
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Humans
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Immunoenzyme Techniques
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Infant
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Microscopy, Electron
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Parietal Lobe / pathology
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Parietal Lobe / surgery*
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Temporal Lobe / pathology
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Temporal Lobe / surgery*
Substances
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Glial Fibrillary Acidic Protein