Abstract
[reaction: see text] The Horner-Wadsworth-Emmons reaction of aldehydes with sulfinimine-derived 3-oxo pyrrolidine phosphonates represents a new method for the asymmetric synthesis of ring-functionalized cis-2,5-disubstituted 3-oxo pyrrolidines.
Publication types
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Research Support, N.I.H., Extramural
MeSH terms
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Aldehydes / chemistry
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Catalysis
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Imines / chemistry
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Molecular Structure
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Organophosphonates / chemistry*
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Pyrrolidines / chemical synthesis*
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Pyrrolidines / chemistry*
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Stereoisomerism
Substances
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Aldehydes
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Imines
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Organophosphonates
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Pyrrolidines
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pyrrolidine 225C