Abstract
In this study, largemouth bass (LMB) were subchronically exposed to p,p'-DDE or dieldrin in their diet to evaluate the effect of exposure on expression of genes involved in reproduction and steroid homeostasis. Using real-time PCR, we detected a different gene expression pattern for each OCP, suggesting that they each affect LMB in a different way. We also detected a different expression pattern among sexes, suggesting that sexes are affected differently by OCPs perhaps reflecting the different adaptive responses of each sex to dysregulation caused by OCP exposure.
Publication types
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Comparative Study
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Bass / genetics*
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Bass / metabolism
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Dichlorodiphenyl Dichloroethylene / toxicity*
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Dieldrin / toxicity*
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Female
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Gene Expression / drug effects*
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Gene Expression Profiling / methods
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Gonads / drug effects
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Gonads / enzymology
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Insecticides / toxicity*
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Liver / drug effects
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Liver / enzymology
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Male
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RNA, Messenger / analysis
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RNA, Messenger / biosynthesis
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Sex Factors
Substances
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Insecticides
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RNA, Messenger
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Dichlorodiphenyl Dichloroethylene
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Dieldrin