Statins in patients with chronic kidney disease: evidence from systematic reviews and randomized clinical trials

Sankar D Navaneethan; Francesca Pansini; Giovanni F M Strippoli

doi:10.1371/journal.pmed.0030123

Statins in patients with chronic kidney disease: evidence from systematic reviews and randomized clinical trials

PLoS Med. 2006 May;3(5):e123. doi: 10.1371/journal.pmed.0030123. Epub 2006 May 30.

Authors

Sankar D Navaneethan¹, Francesca Pansini, Giovanni F M Strippoli

Affiliation

¹ Department of Medicine, Unity Health System, Rochester, New York, United States of America. [email protected]

Abstract

Good evidence supports the widespread use of statins for cardiovascular disease; there is less evidence for their use in kidney disease. The question is addressed by discussing published trials and systematic reviews.

Publication types

Review

MeSH terms

Cardiovascular Diseases / prevention & control*
Cholesterol, LDL / drug effects
Chronic Disease
Dialysis
Humans
Hydroxymethylglutaryl-CoA Reductase Inhibitors / adverse effects*
Hydroxymethylglutaryl-CoA Reductase Inhibitors / therapeutic use*
Hypercholesterolemia / complications
Hypercholesterolemia / drug therapy*
Kidney Diseases / complications*
Kidney Diseases / therapy
Kidney Transplantation
Randomized Controlled Trials as Topic

Substances

Cholesterol, LDL
Hydroxymethylglutaryl-CoA Reductase Inhibitors