Dancin' deaminase

Nat Struct Mol Biol. 2006 May;13(5):380-1. doi: 10.1038/nsmb0506-380.

Abstract

New biochemical experiments with the retroelement restriction protein APOBEC3G indicate that it processively deaminates single-stranded DNA cytosines by a unique jumping and sliding mechanism.

Publication types

  • News
  • Comment

MeSH terms

  • APOBEC-3G Deaminase
  • Cytidine Deaminase
  • Cytosine / chemistry
  • Cytosine / metabolism
  • Cytosine Deaminase / metabolism
  • DNA / genetics
  • DNA / metabolism
  • Deamination
  • Humans
  • Mutation / genetics
  • Nucleoside Deaminases / genetics
  • Nucleoside Deaminases / metabolism*
  • Repressor Proteins / genetics
  • Repressor Proteins / metabolism*

Substances

  • Repressor Proteins
  • Cytosine
  • DNA
  • Nucleoside Deaminases
  • Cytosine Deaminase
  • APOBEC-3G Deaminase
  • APOBEC3G protein, human
  • Cytidine Deaminase