Development of antibodies to Burkholderia pseudomallei during childhood in melioidosis-endemic northeast Thailand

Am J Trop Med Hyg. 2006 Jun;74(6):1074-5.

Abstract

A cross-sectional serological survey of 2,214 children living in northeast Thailand was conducted to define the antibody response to Burkholderia pseudomallei from birth to 14 years. There was a sharp rise in detectable antibodies from birth to 4 years followed by reactivity in approximately 60-70% of children thereafter.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Age Factors
  • Antibodies, Bacterial / blood*
  • Antibodies, Bacterial / immunology
  • Burkholderia pseudomallei / immunology*
  • Child
  • Child, Preschool
  • Cross-Sectional Studies
  • Endemic Diseases*
  • Female
  • Humans
  • Infant
  • Male
  • Melioidosis / epidemiology
  • Melioidosis / immunology*
  • Prevalence
  • Prospective Studies
  • Seroepidemiologic Studies
  • Thailand / epidemiology
  • Time Factors

Substances

  • Antibodies, Bacterial