Chemo-differentiating MCRs based on alpha-ketoesters and terminal alkynoates. A homoaldol-based ABB' system

Chem Commun (Camb). 2006 Jul 5:(25):2667-9. doi: 10.1039/b605075a. Epub 2006 May 18.

Abstract

A novel ABB' 3 component reaction (3-CR) system based on the organocatalyzed homoaldolic condensation of alpha-ketoesters in the presence of terminal conjugated alkynoates is described.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aldehydes / chemistry*
  • Alkynes / chemistry*
  • Catalysis
  • Esters / chemistry*
  • Ethylamines / chemistry
  • Ketones / chemistry*
  • Methylation
  • Molecular Structure
  • Propionates / chemistry

Substances

  • Aldehydes
  • Alkynes
  • Esters
  • Ethylamines
  • Ketones
  • Propionates
  • 3-hydroxybutanal
  • propiolic acid
  • triethylamine