Transcription. Gene expression needs a break to unwind before carrying on

Science. 2006 Jun 23;312(5781):1752-3. doi: 10.1126/science.1129808.
No abstract available

Publication types

  • Comment

MeSH terms

  • Chromatin / chemistry
  • Chromatin / metabolism
  • DNA / metabolism*
  • DNA Repair
  • DNA Topoisomerases, Type II / metabolism*
  • DNA-Activated Protein Kinase / metabolism
  • DNA-Binding Proteins / antagonists & inhibitors
  • DNA-Binding Proteins / metabolism*
  • Enzyme Activation
  • Gene Expression
  • Histones / metabolism
  • Humans
  • Models, Genetic
  • Nucleosomes / metabolism
  • Phosphorylation
  • Poly (ADP-Ribose) Polymerase-1
  • Poly Adenosine Diphosphate Ribose / metabolism
  • Poly(ADP-ribose) Polymerases / metabolism*
  • Response Elements
  • Topoisomerase II Inhibitors
  • Transcription Factors / metabolism
  • Transcription, Genetic*
  • Transcriptional Activation*

Substances

  • Chromatin
  • DNA-Binding Proteins
  • Histones
  • Nucleosomes
  • Topoisomerase II Inhibitors
  • Transcription Factors
  • Poly Adenosine Diphosphate Ribose
  • DNA
  • PARP1 protein, human
  • Poly (ADP-Ribose) Polymerase-1
  • Poly(ADP-ribose) Polymerases
  • DNA-Activated Protein Kinase
  • DNA Topoisomerases, Type II