Breast-feeding in a woman with cystic fibrosis undergoing antibiotic intravenous treatment

J Matern Fetal Neonatal Med. 2006 Jun;19(6):375-6. doi: 10.1080/14767050600631468.

Abstract

We report the case of a 30-year-old woman with cystic fibrosis (CF) chronically infected with Pseudomonas aeruginosa who delivered and breast-fed a healthy boy. While breast-feeding the woman had to undergo an i.v. antibiotic course with tobramycin, due to pulmonary exacerbation. Tobramycin was not detected in her milk and lactation could be continued. This is the first time that the presence of tobramycin in the milk of a CF woman during i.v. administration has been investigated.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Anti-Bacterial Agents / administration & dosage
  • Anti-Bacterial Agents / blood
  • Anti-Bacterial Agents / metabolism
  • Anti-Bacterial Agents / therapeutic use
  • Cystic Fibrosis*
  • Diagnosis, Differential
  • Female
  • Humans
  • Infant, Newborn
  • Infusions, Intravenous
  • Male
  • Milk, Human / metabolism*
  • Pregnancy
  • Pregnancy Complications, Infectious / diagnosis*
  • Pregnancy Complications, Infectious / drug therapy
  • Pregnancy Complications, Infectious / pathology
  • Prenatal Diagnosis*
  • Pseudomonas Infections / diagnosis*
  • Pseudomonas Infections / drug therapy
  • Pseudomonas Infections / pathology
  • Tobramycin / administration & dosage
  • Tobramycin / blood
  • Tobramycin / metabolism
  • Tobramycin / therapeutic use

Substances

  • Anti-Bacterial Agents
  • Tobramycin