Four novel gelsenicine-related oxindole alkaloids from the leaves of Gelsemium elegans benth

Noriyuki Kogure; Naoko Ishii; Mariko Kitajima; Sumphan Wongseripipatana; Hiromitsu Takayama

doi:10.1021/ol061062i

Four novel gelsenicine-related oxindole alkaloids from the leaves of Gelsemium elegans benth

Org Lett. 2006 Jul 6;8(14):3085-8. doi: 10.1021/ol061062i.

Authors

Noriyuki Kogure¹, Naoko Ishii, Mariko Kitajima, Sumphan Wongseripipatana, Hiromitsu Takayama

Affiliation

¹ Graduate School of Pharmaceutical Sciences, Chiba University, Inage-ku, Japan.

PMID: 16805558
DOI: 10.1021/ol061062i

Abstract

[reaction: see text] New types of four gelsenicine-related oxindole alkaloids were isolated from the leaves of Gelsemium elegans Benth. Gelsedilam (1) and 14-acetoxygelsedilam (2) are the first examples of 18,19-nor-type monoterpenoid indole alkaloids. Gelsefuranidine (3) and gelseiridone (4) have, respectively, an additional furan residue or an iridoid unit on the gelsenicine-related monoterpenoid indole alkaloid.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Gelsemium / chemistry*
Molecular Structure
Plant Leaves / chemistry
Plants, Medicinal / chemistry*
Secologanin Tryptamine Alkaloids / chemistry*
Secologanin Tryptamine Alkaloids / isolation & purification*
Thailand

Substances

Secologanin Tryptamine Alkaloids