Molecular genetics of the debrisoquin-sparteine polymorphism

Clin Pharmacol Ther. 1991 Sep;50(3):233-8. doi: 10.1038/clpt.1991.131.
No abstract available

Publication types

  • Review

MeSH terms

  • Alleles*
  • Chromosome Mapping
  • Cytochrome P-450 Enzyme System / deficiency
  • Cytochrome P-450 Enzyme System / genetics*
  • Debrisoquin / metabolism*
  • Genotype
  • Humans
  • Mutation
  • Pharmacogenetics
  • Polymorphism, Genetic / genetics*
  • Polymorphism, Restriction Fragment Length
  • Sparteine / metabolism*

Substances

  • Sparteine
  • Cytochrome P-450 Enzyme System
  • Debrisoquin