RNAKinetics: a web server that models secondary structure kinetics of an elongating RNA

J Bioinform Comput Biol. 2006 Apr;4(2):589-96. doi: 10.1142/s0219720006001904.

Abstract

The RNAKinetics server (http://www.ig-msk.ru/RNA/kinetics) is a web interface for the newly developed RNAKinetics software. The software models the dynamics of RNA secondary structure by the means of kinetic analysis of folding transitions of a growing RNA molecule. The result of the modeling is a kinetic ensemble, i.e. a collection of RNA structures that are endowed with probabilities, which depend on time. This approach gives comprehensive probabilistic description of RNA folding pathways, revealing important kinetic details that are not captured by the traditional structure prediction methods. The access to the RNAKinetics server is free.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Base Sequence
  • Computer Graphics
  • Computer Simulation
  • Kinetics
  • Models, Chemical*
  • Models, Molecular*
  • Molecular Sequence Data
  • Motion
  • Nucleic Acid Conformation
  • RNA / chemistry*
  • Sequence Analysis, RNA / methods*
  • Software*
  • User-Computer Interface*

Substances

  • RNA