A collection of dosage forms is presented, which are currently used in the treatment of cardiovascular and circulatory diseases including rarely used dosage forms. For each form important details to be considered during application are listed which are based on individual properties of the specific dosage form. Furthermore, general recommendations on the application of cardiovascular drugs are presented as well as information on dividing and crushing of dosage forms for dose reduction or application via tube, which is permitted for instant release dosage forms whereas modified release systems restrict the ability to divide or crush. Another chapter summarizes the prerequisites for a safe substitution of drugs which requires consideration of the particular dosage form.