Identification of twelve new RFLP-markers on chromosome 22q11-qter

Hum Genet. 1991 Dec;88(2):135-8. doi: 10.1007/BF00206060.

Abstract

We have previously identified and regionally localized 195 chromosome-22-specific DNA markers. We now report restriction fragment length polymorphisms detected by 9 phage markers mapped to 22q11-q12, two cosmid clones mapped to 22q12-q13 and one plasmid mapped to 22q13-qter. These markers may be useful tools for mapping disease genes such as the NF2 locus, on chromosome 22.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alleles
  • Blotting, Southern
  • Chromosomes, Human, Pair 22*
  • Cloning, Molecular
  • Cosmids / genetics
  • DNA Restriction Enzymes / metabolism
  • Genetic Markers / genetics*
  • Humans
  • Polymorphism, Restriction Fragment Length*

Substances

  • Genetic Markers
  • DNA Restriction Enzymes