Similarities and differences in interactions of the activity-enhancing chemoreceptor pentapeptide with the two enzymes of adaptational modification

J Bacteriol. 2006 Aug;188(15):5646-9. doi: 10.1128/JB.00497-06.

Abstract

Sensory adaptation and chemotaxis by Escherichia coli require a specific pentapeptide at the chemoreceptor carboxyl terminus. This sequence binds the two enzymes of receptor adaptational modification, enhancing catalysis, but with different binding features and mechanisms. We investigated the relative importance of each pentapeptide side chain for the two enhancing interactions.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Binding Sites
  • Chemotaxis
  • Electrophoresis, Polyacrylamide Gel
  • Escherichia coli / metabolism*
  • Escherichia coli / physiology
  • Escherichia coli Proteins / analysis
  • Escherichia coli Proteins / metabolism*
  • Methylation
  • Methyltransferases / analysis
  • Methyltransferases / metabolism*
  • Oligopeptides / chemistry
  • Oligopeptides / metabolism*
  • Peptides / metabolism*
  • Signal Transduction*

Substances

  • Escherichia coli Proteins
  • Oligopeptides
  • Peptides
  • Methyltransferases