Microinjection of S-nitrosocysteine into the nucleus tractus solitarii decreases arterial pressure and heart rate via activation of soluble guanylate cyclase

Eur J Pharmacol. 1991 Sep 4;202(1):135-6. doi: 10.1016/0014-2999(91)90269-v.
No abstract available

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Blood Pressure / drug effects*
  • Cysteine / administration & dosage
  • Cysteine / analogs & derivatives*
  • Cysteine / pharmacology
  • Depression, Chemical
  • Enzyme Activation / drug effects
  • Guanylate Cyclase / metabolism*
  • Heart Rate / drug effects*
  • Male
  • Medulla Oblongata*
  • Methylene Blue / pharmacology
  • Microinjections
  • Neurons, Afferent / drug effects
  • Rats
  • Rats, Inbred Strains
  • S-Nitrosothiols*

Substances

  • S-Nitrosothiols
  • S-nitrosocysteine
  • Guanylate Cyclase
  • Cysteine
  • Methylene Blue