Inhibitory effects of a platelet activating factor-antagonist 48740RP in cyclosporin-induced nephrotoxicity in the rat as assessed by renal glutathione metabolism parameters

Arch Toxicol Suppl. 1991:14:213-7. doi: 10.1007/978-3-642-74936-0_44.

Authors

F Massicot¹, C Pham Huy, C Martin, M Thevenin, J M Warnet, J R Claude

Affiliation

¹ Laboratoire de Toxicologie, Faculté de Pharmacie, Paris, France.

PMID: 1687197
DOI: 10.1007/978-3-642-74936-0_44

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Aminopeptidases / metabolism
Animals
Blood Urea Nitrogen
CD13 Antigens
Creatinine / blood
Cyclosporine / toxicity*
Glutathione / metabolism*
Kidney / drug effects*
Kidney / metabolism
Kidney Cortex / drug effects
Kidney Cortex / metabolism
Platelet Activating Factor / antagonists & inhibitors*
Pyridines / pharmacology*
Rats
Thiazoles / pharmacology*

Substances

Platelet Activating Factor
Pyridines
Thiazoles
Cyclosporine
3-(3-pyridinyl)-1H,3H-pyrrolo(1,2-c)thiazole-7-carboxamide
Creatinine
Aminopeptidases
CD13 Antigens
Glutathione