Abstract
In Drosophila, the RNA interference (RNAi) genes participate in Polycomb (Pc)-mediated transgene silencing. Recently, the involvement of the RNAi genes in Pc silencing, pairing-sensitive silencing and long-range contacts among Pc-associated sequences has been explored. These Pc-associated sequences are involved with the control of the proper expression of developmental HOX genes.
Publication types
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Research Support, U.S. Gov't, Non-P.H.S.
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Comment
MeSH terms
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Animals
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Argonaute Proteins
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Cell Nucleus / metabolism
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Chromosome Pairing*
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Drosophila Proteins / genetics
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Drosophila Proteins / metabolism*
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Drosophila melanogaster / genetics*
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Drosophila melanogaster / metabolism
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Models, Genetic
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Polycomb Repressive Complex 1
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Proteins / metabolism*
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RNA Interference*
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RNA-Induced Silencing Complex
Substances
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Argonaute Proteins
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Drosophila Proteins
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Pc protein, Drosophila
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Proteins
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RNA-Induced Silencing Complex
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piwi protein, Drosophila
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Polycomb Repressive Complex 1