The effects of N-acetylcysteine on methotrexate-induced oxidative renal damage in rats

Nephrol Dial Transplant. 2007 Jan;22(1):284-5. doi: 10.1093/ndt/gfl420. Epub 2006 Jul 28.
No abstract available

Publication types

  • Letter

MeSH terms

  • Acetylcysteine / metabolism*
  • Animals
  • Antioxidants / metabolism
  • Glutathione / metabolism
  • Humans
  • Kidney / drug effects
  • Kidney / metabolism
  • Kidney / pathology*
  • Kidney Diseases / chemically induced*
  • Kidney Diseases / pathology
  • Methotrexate / adverse effects
  • Methotrexate / pharmacology*
  • Oxidants / metabolism
  • Oxidation-Reduction
  • Oxidative Stress
  • Rats
  • Rats, Wistar

Substances

  • Antioxidants
  • Oxidants
  • Glutathione
  • Acetylcysteine
  • Methotrexate