Abstract
Water-soluble H-CNFs modified with a carboxyl group possessed the ability to induce TNF-alpha, whereas CHAPS-treated H-CNFs possessed significantly greater activity and were also found to activate NF-kappaB reporter activity, to a significantly greater level than H-CNFs; furthermore the functional group modified or coated on the surface of H-CNFs was a significant cytotoxic factor that affected cell activation.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Carbon / chemistry*
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Carbon / pharmacology
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Cell Line
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Humans
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Materials Testing
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Microscopy, Electron, Scanning
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Monocytes / cytology
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Monocytes / drug effects
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Monocytes / metabolism
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NF-kappa B / metabolism
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Nanostructures / chemistry*
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Nanotechnology
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Solubility
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Spectrophotometry, Infrared
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Structure-Activity Relationship
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Tumor Necrosis Factor-alpha / metabolism
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Water / chemistry
Substances
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NF-kappa B
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Tumor Necrosis Factor-alpha
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Water
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Carbon